8 Transcriptional Regulation during Somitogenesis

D Summerbell, PWJ Rigby - Current Topics in Developmental Biology, 1999 - Elsevier
Publisher Summary This chapter discusses the biochemical mechanisms involved in the
regulation of transcription during the development of the mouse embryo. General approach
for this study involves taking genes known to act at a fairly high level in a particular genetic
pathway and then to try to understand how their transcription is controlled using the power of
transgenic mouse technology. In each case the objective is to identify of each of the
transcription factors that control the chosen regulatory gene. It is reported that segmental …