New disguises for an old channel: MaxiK channel β-subunits
Physiology, 2002•journals.physiology.org
Ca2+-activated K+ channels of large conductance (MaxiK or BK channels) control a large
variety of physiological processes, including smooth muscle tone, neurosecretion, and
hearing. Despite being coded by a single gene (Slowpoke), the diversity of MaxiK channels
is great. Regulatory b-subunits, splicing, and metabolic regulation create this diversity
fundamental to the adequate function of many tissues.
variety of physiological processes, including smooth muscle tone, neurosecretion, and
hearing. Despite being coded by a single gene (Slowpoke), the diversity of MaxiK channels
is great. Regulatory b-subunits, splicing, and metabolic regulation create this diversity
fundamental to the adequate function of many tissues.
Ca2+-activated K+ channels of large conductance (MaxiK or BK channels) control a large variety of physiological processes, including smooth muscle tone, neurosecretion, and hearing. Despite being coded by a single gene (Slowpoke), the diversity of MaxiK channels is great. Regulatory b-subunits, splicing, and metabolic regulation create this diversity fundamental to the adequate function of many tissues.
American Physiological Society