The etiology of Alzheimer disease (AD) is not well understood; therefore, neither prevention
strategies nor long-term effective treatment modalities are available for this disease. Based
on laboratory and clinical studies, it appears that reactive oxygen species (ROS) and
reactive nitrogen species (RNS) that are generated extracellularly and intracellularly by
various mechanisms are among the major intermediary risk factors that initiate and promote
neurodegeneration in idiopathic AD. Therefore, multiple antioxidant supplements could be …