Age-related change in the potential of bone marrow cells to repopulate the thymus and splenic T cells in mice
K Hirokawa, S Kubo, M Utsuyama, C Kurashima… - Cellular …, 1986 - Elsevier
Bone marrow chimeras were produced between various combinations of young and old
mice using either C57BL/6 mice only or a combination of C57BL/6 and B10. Thy-1.1 mice.
The wet weight of the thymus and the number of thymocytes and splenic T cells of donor
origin were assessed at appropriate intervals after the bone marrow transplantation. It was
revealed that the old bone marrow was inferior to young in terms of the capacity to
repopulate the thymus and splenic T cells. Moreover, some age-related qualitative changes …
mice using either C57BL/6 mice only or a combination of C57BL/6 and B10. Thy-1.1 mice.
The wet weight of the thymus and the number of thymocytes and splenic T cells of donor
origin were assessed at appropriate intervals after the bone marrow transplantation. It was
revealed that the old bone marrow was inferior to young in terms of the capacity to
repopulate the thymus and splenic T cells. Moreover, some age-related qualitative changes …
