Lipid peroxidation and oxidation of several compounds by H2O2 activated metmyoglobin

J Kanner, S Harel - Lipids, 1985 - Springer
J Kanner, S Harel
Lipids, 1985Springer
Activated metmyoglobin (MetMb) by H 2 O 2 initiates oxidation of microsomal unsaturated
fatty acids, β-carotene and methional but not formate. Lipid peroxidation by activated MetMb
was not inhibited by catalase. The activated species which initiaes lipid peroxidation
appears to be a porphyrin cation radical, P∸+ Fe IV= O, and not a hydroxyl radical.
Abstract
Activated metmyoglobin (MetMb) by H2O2 initiates oxidation of microsomal unsaturated fatty acids, β-carotene and methional but not formate. Lipid peroxidation by activated MetMb was not inhibited by catalase. The activated species which initiaes lipid peroxidation appears to be a porphyrin cation radical, P + FeIV=O, and not a hydroxyl radical.
Springer