[HTML][HTML] Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects

LC Hudgins, MK Hellerstein, CE Seidman… - Journal of lipid …, 2000 - ASBMB
We previously reported that a eucaloric, low fat, liquid formula diet enriched in simple
carbohydrate markedly increased the synthesis of fatty acids in lean volunteers. To examine
the diet sensitivity of obese subjects, 7 obese and 12 lean volunteers were given two
eucaloric low fat solid food diets enriched in simple sugars for 2 weeks each in a random-
order, cross-over design (10% fat, 75% carbohydrate vs. 30% fat, 55% carbohydrate, ratio of
sugar to starch 60: 40). The fatty acid compositions of both diets were matched to the …