The pathogenesis and treatment of kidney stones

FL Coe, JH Parks, JR Asplin - New England Journal of Medicine, 1992 - Mass Medical Soc
FL Coe, JH Parks, JR Asplin
New England Journal of Medicine, 1992Mass Medical Soc
ABOUT three fourths of all kidney stones are composed of calcium oxalate1; most calcium
oxalate stones also contain a small amount of hydroxyapatite, and 10 to 12 percent contain
some uric acid. 2 Ten to 20 percent of stones contain struvite (magnesium ammonium
phosphate) produced by a urinary tract infection with bacteria that express the enzyme
urease. 3 Five percent of stones are pure uric acid, 5 percent contain more than 50 percent
hydroxyapatite or calcium monohydrogen phosphate (brushite), and less than 1 percent are …
ABOUT three fourths of all kidney stones are composed of calcium oxalate1; most calcium oxalate stones also contain a small amount of hydroxyapatite, and 10 to 12 percent contain some uric acid.2 Ten to 20 percent of stones contain struvite (magnesium ammonium phosphate) produced by a urinary tract infection with bacteria that express the enzyme urease.3 Five percent of stones are pure uric acid, 5 percent contain more than 50 percent hydroxyapatite or calcium monohydrogen phosphate (brushite), and less than 1 percent are composed of cystine. Whereas most calcium oxalate stones are less than 2 cm in diameter, struvite, . . .
The New England Journal Of Medicine