[HTML][HTML] Effects of age on DNA double-strand breaks and apoptosis in human sperm
NP Singh, CH Muller, RE Berger - Fertility and sterility, 2003 - Elsevier
OBJECTIVE: This study was designed to explore the relationship between men's age and
DNA damage and apoptosis in human spermatozoa. DESIGN: Semen samples were
collected from men between the ages of 20 and 57 years. Sperm DNA double-strand breaks
were assessed using the neutral microgel electrophoresis (comet) assay, and apoptosis was
estimated using the DNA diffusion assay. SETTING: Academic medical center. PATIENT (S):
Sixty-six men aged 20 to 57 years were recruited from infertility laboratory and general …
DNA damage and apoptosis in human spermatozoa. DESIGN: Semen samples were
collected from men between the ages of 20 and 57 years. Sperm DNA double-strand breaks
were assessed using the neutral microgel electrophoresis (comet) assay, and apoptosis was
estimated using the DNA diffusion assay. SETTING: Academic medical center. PATIENT (S):
Sixty-six men aged 20 to 57 years were recruited from infertility laboratory and general …
