Biological characteristics of the globular substance in the otoconial membrane of the guinea pig

H Suzuki, K Ikeda, T Takasaka - Hearing research, 1995 - Elsevier
Biological characteristics of the globular substance, which is considered to be a precursor of
otoconia, were investigated by means of confocal laser scanning microscopy. The shape of
the globular substance was a complete sphere, 3–10 μm in diameter. Its surface stained
positively with both rhodamine 123 and DiOC6 (3), implying similarity to intracellular
organelles, whereas no fluorescence was seen when stained with chlortetracycline, a
membrane-associated Ca2+ dye. Meanwhile, this substance showed very little affinity for six …