[HTML][HTML] Changes in gray matter density in fibromyalgia: correlation with dopamine metabolism
PB Wood, MF Glabus, R Simpson, JC Patterson 2nd - The Journal of Pain, 2009 - Elsevier
Fibromyalgia (FM) has been associated with alterations in brain morphometry and abnormal
dopaminergic neurotransmission. Evidence from preclinical models has demonstrated that
dopamine plays a role in promoting neuronal integrity. We therefore sought to confirm
previous findings of reduced gray matter density in subjects with FM and to determine
whether variations in dopamine metabolism might affect gray matter density. Voxel-based
morphometry was used to evaluate anatomical magnetic resonance imaging data from 30 …
dopaminergic neurotransmission. Evidence from preclinical models has demonstrated that
dopamine plays a role in promoting neuronal integrity. We therefore sought to confirm
previous findings of reduced gray matter density in subjects with FM and to determine
whether variations in dopamine metabolism might affect gray matter density. Voxel-based
morphometry was used to evaluate anatomical magnetic resonance imaging data from 30 …