Changes in hippocampal metabolites after effective treatment for fibromyalgia: a case study
PB Wood, CR Ledbetter, JC Patterson - The Clinical journal of …, 2009 - journals.lww.com
Background Fibromyalgia has been associated with disrupted hippocampal brain metabolite
ratios by studies using single voxel magnetic resonance spectroscopy (1H-MRS). Exposure
to stress is considered a risk factor for the development and exacerbation of fibromyalgia
symptoms. Basic science has demonstrated the hippocampus to be exquisitely sensitive to
the effects of stressful experience, which results in changes including alterations in
metabolite content and frank atrophy. Methods This report details the case of a 47-year-old …
ratios by studies using single voxel magnetic resonance spectroscopy (1H-MRS). Exposure
to stress is considered a risk factor for the development and exacerbation of fibromyalgia
symptoms. Basic science has demonstrated the hippocampus to be exquisitely sensitive to
the effects of stressful experience, which results in changes including alterations in
metabolite content and frank atrophy. Methods This report details the case of a 47-year-old …