Determining anatomical connectivities between cortical and brainstem pain processing regions in humans: a diffusion tensor imaging study in healthy controls

G Hadjipavlou, P Dunckley, TE Behrens, I Tracey - Pain, 2006 - Elsevier
Neuroimaging methods have so far identified various structures in the brain involved in the
processing of pain and its control. However, our understanding of their anatomical
connectivities is relatively weak. Diffusion tensor imaging (DTI), a magnetic resonance
imaging-based method, allows in vivo mapping of the anatomical connections in the human
brain and was used to investigate the white matter connections originating from the
periaquaductal grey (PAG) and nucleus cuneiformis (NCF). We performed DTI on 8 healthy …