Neuroimaging studies with positron emission tomography (PET) and functional magnetic
resonance imaging (fMRI) have delineated a human pain network in vivo. Despite the
recognition of cerebral structures engaged in pain transmission, the cerebral mechanisms
involved in pain modulation are still not well understood. Here, we investigated healthy
volunteers using fMRI during experimental heat pain and distraction induced by a visual
incongruent color-word Stroop task. A factorial design permitted categorical and covariation …