Cortical effects of anticipation and endogenous modulation of visceral pain assessed by functional brain MRI in irritable bowel syndrome patients and healthy controls
GH Song, V Venkatraman, KY Ho, MWL Chee… - Pain, 2006 - Elsevier
Visceral pain processing is abnormal in a majority of irritable bowel syndrome (IBS) patients.
Aberrant endogenous nociceptive modulation and anticipation are possible underlying
mechanisms investigated in the current study. Twelve IBS patients and 12 matched healthy
controls underwent brain fMRI scanning during the following randomised stimuli: sham and
painful rectal distensions by barostat without and with simultaneous activation of
endogenous descending nociceptive inhibition using ice water immersion of the foot for …
Aberrant endogenous nociceptive modulation and anticipation are possible underlying
mechanisms investigated in the current study. Twelve IBS patients and 12 matched healthy
controls underwent brain fMRI scanning during the following randomised stimuli: sham and
painful rectal distensions by barostat without and with simultaneous activation of
endogenous descending nociceptive inhibition using ice water immersion of the foot for …