Gray matter decrease in patients with chronic tension type headache
T Schmidt-Wilcke, E Leinisch, A Straube, N Kampfe… - Neurology, 2005 - AAN Enterprises
T Schmidt-Wilcke, E Leinisch, A Straube, N Kampfe, B Draganski, HC Diener, U Bogdahn…
Neurology, 2005•AAN EnterprisesUsing MRI and voxel-based morphometry, the authors investigated 20 patients with chronic
tension type headache (CTTH) and 20 patients with medication-overuse headache and
compared them to 40 controls with no headache history. Only patients with CTTH
demonstrated a significant gray matter decrease in regions known to be involved in pain
processing. The finding implies that the alterations are specific to CTTH rather than a
response to chronic head pain or chronification per se.
tension type headache (CTTH) and 20 patients with medication-overuse headache and
compared them to 40 controls with no headache history. Only patients with CTTH
demonstrated a significant gray matter decrease in regions known to be involved in pain
processing. The finding implies that the alterations are specific to CTTH rather than a
response to chronic head pain or chronification per se.
Using MRI and voxel-based morphometry, the authors investigated 20 patients with chronic tension type headache (CTTH) and 20 patients with medication-overuse headache and compared them to 40 controls with no headache history. Only patients with CTTH demonstrated a significant gray matter decrease in regions known to be involved in pain processing. The finding implies that the alterations are specific to CTTH rather than a response to chronic head pain or chronification per se.
American Academy of Neurology