Diffuse noxious inhibitory controls (DNIC). II. Lack of effect on non-convergent neurones, supraspinal involvement and theoretical implications
D Le Bars, AH Dickenson, J Besson - Pain, 1979 - Elsevier
(1) Diffuse noxious inhibitory controls (DNIC) were tested for their effect on noxious only, non-
noxious and proprioceptive cells in the dorsal horn of the intact anaesthetized rat. Unlike
convergent neurones, as described in the previous paper, there was no effect of DNIC on
these neurones, It is concluded that convergent neurones are specifically inhibited by DNIC.
2.(2) The effect of DNIC could not be demonstrated for convergent neurones in the spinal
animal. Thus the neuronal substrate for DNIC must involve supraspinal structures. 3.(3) …
noxious and proprioceptive cells in the dorsal horn of the intact anaesthetized rat. Unlike
convergent neurones, as described in the previous paper, there was no effect of DNIC on
these neurones, It is concluded that convergent neurones are specifically inhibited by DNIC.
2.(2) The effect of DNIC could not be demonstrated for convergent neurones in the spinal
animal. Thus the neuronal substrate for DNIC must involve supraspinal structures. 3.(3) …