Descending control of pain transmission: possible serotonergic-enkephalinergic interactions
AI Basbaum - Serotonin: Current Aspects of Neurochemistry and …, 1981 - Springer
Serotonin: Current Aspects of Neurochemistry and Function, 1981•Springer
To a somewhat suprising extent, many recent advances in our understanding of the role of
serotonin in pain modulation derive more from anatomical and physiological studies than
from pharmacological and behavioral analyses. This has resulted, in part, from the
development of new anatomical methods for the localization of CNS monoamines.
Concurrently, the development of methods for the localization of putative CNS transmitter
peptides has allowed an analysis of possible interactions between, for example, serotonin …
serotonin in pain modulation derive more from anatomical and physiological studies than
from pharmacological and behavioral analyses. This has resulted, in part, from the
development of new anatomical methods for the localization of CNS monoamines.
Concurrently, the development of methods for the localization of putative CNS transmitter
peptides has allowed an analysis of possible interactions between, for example, serotonin …
Abstract
To a somewhat suprising extent, many recent advances in our understanding of the role of serotonin in pain modulation derive more from anatomical and physiological studies than from pharmacological and behavioral analyses. This has resulted, in part, from the development of new anatomical methods for the localization of CNS monoamines. Concurrently, the development of methods for the localization of putative CNS transmitter peptides has allowed an analysis of possible interactions between, for example, serotonin, enkephalin and substance P.
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