Aβ-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals
L Djouhri, SN Lawson - Brain research reviews, 2004 - Elsevier
The existence of nociceptors with Aβ-fibers has often been overlooked, and many textbooks
endorse the view that all nociceptors have either C-or Aδ-fibers. Here we review evidence
starting from the earliest descriptions of A-fiber nociceptors, which clearly indicates that a
substantial proportion of cutaneous/somatic afferent A-fiber nociceptors conduct in the Aβ
conduction velocity (CV) range in all species in which CV was carefully examined, including
mouse, rat, guinea pig, cat and monkey. Reported proportions of A-fiber nociceptors with Aβ …
endorse the view that all nociceptors have either C-or Aδ-fibers. Here we review evidence
starting from the earliest descriptions of A-fiber nociceptors, which clearly indicates that a
substantial proportion of cutaneous/somatic afferent A-fiber nociceptors conduct in the Aβ
conduction velocity (CV) range in all species in which CV was carefully examined, including
mouse, rat, guinea pig, cat and monkey. Reported proportions of A-fiber nociceptors with Aβ …