Transient receptor potential channelopathies
B Nilius, G Owsianik - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
B Nilius, G Owsianik
Pflügers Archiv-European Journal of Physiology, 2010•SpringerIn the past years, several hereditary diseases caused by defects in transient receptor
potential channels (TRP) genes have been described. This review summarizes our current
knowledge about TRP channelopathies and their possible pathomechanisms. Based on
available genetic indications, we will also describe several putative pathological conditions
in which (mal) function of TRP channels could be anticipated.
potential channels (TRP) genes have been described. This review summarizes our current
knowledge about TRP channelopathies and their possible pathomechanisms. Based on
available genetic indications, we will also describe several putative pathological conditions
in which (mal) function of TRP channels could be anticipated.
Abstract
In the past years, several hereditary diseases caused by defects in transient receptor potential channels (TRP) genes have been described. This review summarizes our current knowledge about TRP channelopathies and their possible pathomechanisms. Based on available genetic indications, we will also describe several putative pathological conditions in which (mal)function of TRP channels could be anticipated.
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