Short-term efficacy of pharmacotherapeutic interventions in osteoarthritic knee pain: A meta-analysis of randomised placebo-controlled trials
JM Bjordal, A Klovning, AE Ljunggren… - European Journal of Pain, 2007 - Elsevier
BACKGROUND: Pain is the most debilitating symptom in osteoarthritis of the knee (OAK).
AIM AND METHODS: To determine the short-term pain-relieving effects of seven commonly
used pharmacological agents for OAK pain by performing a systematic review of
randomised placebo-controlled trials. RESULTS: In total, 14,060 patients in 63 trials were
evaluated. Opioids and oral NSAIDs therapy in patients with moderate to severe pain (mean
baseline 64.3 and 72.8 mm on VAS respectively) had maximum efficacies compared to …
AIM AND METHODS: To determine the short-term pain-relieving effects of seven commonly
used pharmacological agents for OAK pain by performing a systematic review of
randomised placebo-controlled trials. RESULTS: In total, 14,060 patients in 63 trials were
evaluated. Opioids and oral NSAIDs therapy in patients with moderate to severe pain (mean
baseline 64.3 and 72.8 mm on VAS respectively) had maximum efficacies compared to …