Evidence that was obtained in several experimental models and in strains of hypertensive
rats indicates that infiltration of inflammatory cells and oxidative stress in the kidney play a
role in the induction and maintenance of hypertension. Similar evidence is lacking in human
hypertension, at least in part, because immunosuppressive treatment is unjustified in
patients with hypertension. For addressing this issue, patients who were prescribed by their
private physicians mycophenolate mofetil (MMF) for the treatment of psoriasis or rheumatoid …