Effective treatment of severe asthma is a major unmet need because patients' symptoms are
not controlled on maximum treatment with inhaled therapy. Asthma symptoms can be poorly
controlled because of poor adherence to controller therapy, and this might be addressed by
using combination inhalers that contain a corticosteroid and long-acting β2-agonist as
reliever therapy in addition to maintenance treatment. New bronchodilators with a longer
duration of action are in development, and recent studies have demonstrated the benefit of a …