[HTML][HTML] Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification

ALA Katzenstein, JL Myers - … journal of respiratory and critical care …, 1998 - atsjournals.org
ALA Katzenstein, JL Myers
American journal of respiratory and critical care medicine, 1998atsjournals.org
BACKGROUND Although Hamman and Rich described the pathologic features of four
patients with unexplained interstitial pneumonia in 1944 (5), it was not until the 1960s that
the interstitial pneumonias began to be studied in depth. Renewed interest at that time was
fueled in part by the increased availability of lung biopsy specimens. Liebow (6) was the first
to critically examine the pathologic features of the interstitial pneumonias, dividing them into
five groups based on specific histologic criteria (Table 1). Other investigators, including …
BACKGROUND
Although Hamman and Rich described the pathologic features of four patients with unexplained interstitial pneumonia in 1944 (5), it was not until the 1960s that the interstitial pneumonias began to be studied in depth. Renewed interest at that time was fueled in part by the increased availability of lung biopsy specimens. Liebow (6) was the first to critically examine the pathologic features of the interstitial pneumonias, dividing them into five groups based on specific histologic criteria (Table 1). Other investigators, including Scadding and Hinson (7), Stack and colleagues (8), DeRemee and associates (9), Crystal and associates (10), Winterbauer and coworkers (11), and Turner–Warwick and colleagues (12), were also studying these diseases, and lumped them into a single entity using a variety of terms, including diffuse interstitial fibrosis, diffuse fibrosing alveolitis, cryptogenic fibrosing alveolitis, classical interstitial pneumonitis-fibrosis, diffuse interstitial pneumonitis and IPF. In recent years, the terms IPF and cryptogenic fibrosing alveolitis have become the accepted nomenclature.
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