[HTML][HTML] Past and present definitions of epileptogenesis and its biomarkers

A Pitkänen, J Engel Jr - Neurotherapeutics, 2014 - Elsevier
Descriptions of epileptic seizures and epilepsy date back to antiquity, and research into
fundamental mechanisms of epilepsy in animal models, as well as patients, has been
carried out for over a century. Studies of epileptogenesis, however, as distinct from
ictogenesis, have been pursued for only a few decades, and antiepileptogenesis, the
prevention of epilepsy or its progression, and the reversal of the epileptogenic process or
cure, are relatively recent interests of the basic research community. The goal to develop …