The ISHLT working formulation for pathologic diagnosis of antibody-mediated rejection in heart transplantation: evolution and current status (2005–2011)
GJ Berry, A Angelini, MM Burke, P Bruneval… - The Journal of heart …, 2011 - jhltonline.org
Background The pathogenesis of acute cardiac allograft rejection involves cell-mediated
and antibody-mediated immunologic mechanisms of action. The endomyocardial biopsy
(EMB) diagnosis of acute cellular rejection (ACR), using internationally standardized criteria
has served as a therapeutic target and been accepted as an effective surrogate for cardiac
allograft outcomes.
and antibody-mediated immunologic mechanisms of action. The endomyocardial biopsy
(EMB) diagnosis of acute cellular rejection (ACR), using internationally standardized criteria
has served as a therapeutic target and been accepted as an effective surrogate for cardiac
allograft outcomes.