Banff study of pathologic changes in lung allograft biopsy specimens with donor-specific antibodies

WD Wallace, N Li, CB Andersen, AV Arrossi… - The Journal of Heart and …, 2016 - Elsevier
Background The diagnosis of antibody-mediated rejection (AMR) in the lung transplant is
still an area under investigation. We performed a blinded multicenter study to determine if
any statistically significant histologic findings in transbronchial biopsy specimens from lung
transplant patients correlate with the presence of donor-specific antibodies (DSAs). Methods
We asked 9 pathologists with experience in lung transplantation to evaluate 161 lung
transplant biopsy specimens for various histologic parameters. The findings were correlated …