New anti-tuberculosis agents amongst known drugs

KEA Lougheed, DL Taylor, SA Osborne, JS Bryans… - Tuberculosis, 2009 - Elsevier
Mycobacterium tuberculosis has an on-going impact on global public health and new
therapeutics to treat tuberculosis are urgently required. The emergence of drug resistant
tuberculosis poses a serious threat to the control of this pathogen, and the development of
drugs that are active against the resistant strains is vital. A medium-throughput assay using
the Alamar Blue reagent was set-up to identify novel inhibitors of M. tuberculosis from a
library of known drugs, for which there has already been extensive research investigating …