Effect of doxycycline on aneurysm growth among patients with small infrarenal abdominal aortic aneurysms: a randomized clinical trial
BT Baxter, J Matsumura, JA Curci, R McBride… - Jama, 2020 - jamanetwork.com
Importance Abdominal aortic aneurysms affect more than 3% of US older adults. Objective
To test whether doxycycline reduces the growth of abdominal aortic aneurysm over 2 years
as measured by maximum transverse diameter. Design, Setting, and Participants Parallel, 2-
group, randomized clinical trial that was conducted at 22 US clinical centers between May
2013 and January 2017, and enrolled patients 50 years or older with small (3.5-5.0 cm for
men, 3.5-4.5 cm for women) infrarenal aneurysms. The final date of follow-up was July 31 …
To test whether doxycycline reduces the growth of abdominal aortic aneurysm over 2 years
as measured by maximum transverse diameter. Design, Setting, and Participants Parallel, 2-
group, randomized clinical trial that was conducted at 22 US clinical centers between May
2013 and January 2017, and enrolled patients 50 years or older with small (3.5-5.0 cm for
men, 3.5-4.5 cm for women) infrarenal aneurysms. The final date of follow-up was July 31 …