Aging and atherosclerosis in the rabbit: 1. Distribution, prevalence and morphology of atherosclerotic lesions
LG Spagnoli, A Orlandi, A Mauriello, G Santeusanio… - Atherosclerosis, 1991 - Elsevier
Aging is considered a risk factor in the pathogenesis of atherosclerosis. It is not clear,
however, whether the relationship between aging and atherosclerosis is the result of
increased susceptibility of the arterial wall related to intrinsic alterations or the expression of
the increase in intensity or duration of exposure to risk factors. In this study, we used aged
(median age 46 months) and young (4 months old) New Zealand white rabbits. Nine aged
and 11 young rabbits received a hyperlipemic diet enriched with a low dose of cholesterol …
however, whether the relationship between aging and atherosclerosis is the result of
increased susceptibility of the arterial wall related to intrinsic alterations or the expression of
the increase in intensity or duration of exposure to risk factors. In this study, we used aged
(median age 46 months) and young (4 months old) New Zealand white rabbits. Nine aged
and 11 young rabbits received a hyperlipemic diet enriched with a low dose of cholesterol …