Gender determines serum free cortisol: higher levels in men
Y Sofer, E Osher, R Limor, G Shefer, Y Marcus… - Endocrine Practice, 2016 - Elsevier
Objective: Because only the free fraction of serum cortisol can readily access glucocorticoid
receptors, we investigated whether or not a gender-related difference in serum free cortisol
(FC) exists in the basal and adrenocorticotropic hormone (ACTH)-stimulated state. Methods:
Serum total cortisol (TC) and FC were measured in 323 subjects (175 men; 148 women).
Additionally, the low-dose 1-μg ACTH test was performed in 56 subjects (30 women, 26
men). Subjects were healthy volunteers, recruited in a preventive medicine screening …
receptors, we investigated whether or not a gender-related difference in serum free cortisol
(FC) exists in the basal and adrenocorticotropic hormone (ACTH)-stimulated state. Methods:
Serum total cortisol (TC) and FC were measured in 323 subjects (175 men; 148 women).
Additionally, the low-dose 1-μg ACTH test was performed in 56 subjects (30 women, 26
men). Subjects were healthy volunteers, recruited in a preventive medicine screening …