Objectives: Mechanical ventilation is associated with primary diaphragmatic dysfunction,
also termed ventilator-induced diaphragmatic dysfunction. Studies evaluating diaphragmatic
function recovery after extubation are lacking. We evaluated early and late recoveries from
ventilator-induced diaphragmatic dysfunction in a mouse model. Design: Experimental
randomized study. Setting: Research laboratory. Subjects: C57/BL6 mice. Interventions: Six
groups of C57/BL6 mice. Mice were ventilated for 6 hours and then euthanatized …