[HTML][HTML] Grading of adult diffuse gliomas according to the 2021 WHO Classification of Tumors of the Central Nervous System
T Komori - Laboratory Investigation, 2022 - Elsevier
The grading of gliomas based on histological features has been a subject of debate for
several decades. A consensus has not yet been reached because of technical limitations
and inter-observer variations. While the traditional grading system has failed to stratify the
risk of IDH-mutant astrocytoma, canonical histological and proliferative markers may be
applicable to the risk stratification of IDH-wild-type astrocytoma. Numerous studies have
examined molecular markers in order to obtain more clinically relevant information that will …
several decades. A consensus has not yet been reached because of technical limitations
and inter-observer variations. While the traditional grading system has failed to stratify the
risk of IDH-mutant astrocytoma, canonical histological and proliferative markers may be
applicable to the risk stratification of IDH-wild-type astrocytoma. Numerous studies have
examined molecular markers in order to obtain more clinically relevant information that will …
