Tumor-associated B cells in cutaneous primary melanoma and improved clinical outcome
K Garg, M Maurer, J Griss, MC Brüggen, IH Wolf… - Human pathology, 2016 - Elsevier
B cells often infiltrate the microenvironment of human tumors. B cells can both positively and
negatively regulate antitumor immune responses. In several human cancers, higher
numbers of CD20+ TAB are associated with a favorable prognosis, whereas in human
primary melanomas, this association is contentious. In this study, we determined the
association of TAB numbers in cutaneous primary melanoma tissue samples and patients'
overall survival. The CD20 immunohistochemistry on archival nonmetastasized and …
negatively regulate antitumor immune responses. In several human cancers, higher
numbers of CD20+ TAB are associated with a favorable prognosis, whereas in human
primary melanomas, this association is contentious. In this study, we determined the
association of TAB numbers in cutaneous primary melanoma tissue samples and patients'
overall survival. The CD20 immunohistochemistry on archival nonmetastasized and …
