Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial
CM O'Connor, DJ Whellan, KL Lee, SJ Keteyian… - Jama, 2009 - jamanetwork.com
Context Guidelines recommend that exercise training be considered for medically stable
outpatients with heart failure. Previous studies have not had adequate statistical power to
measure the effects of exercise training on clinical outcomes. Objective To test the efficacy
and safety of exercise training among patients with heart failure. Design, Setting, and
Patients Multicenter, randomized controlled trial of 2331 medically stable outpatients with
heart failure and reduced ejection fraction. Participants in Heart Failure: A Controlled Trial …
outpatients with heart failure. Previous studies have not had adequate statistical power to
measure the effects of exercise training on clinical outcomes. Objective To test the efficacy
and safety of exercise training among patients with heart failure. Design, Setting, and
Patients Multicenter, randomized controlled trial of 2331 medically stable outpatients with
heart failure and reduced ejection fraction. Participants in Heart Failure: A Controlled Trial …
Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial
KE Flynn, IL Piña, DJ Whellan, LI Lin, JA Blumenthal… - Jama, 2009 - jamanetwork.com
Context Findings from previous studies of the effects of exercise training on patient-reported
health status have been inconsistent. Objective To test the effects of exercise training on
health status among patients with heart failure. Design, Setting, and Patients Multicenter,
randomized controlled trial among 2331 medically stable outpatients with heart failure with
left ventricular ejection fraction of 35% or less. Patients were randomized from April 2003
through February 2007. Interventions Usual care plus aerobic exercise training (n= 1172) …
health status have been inconsistent. Objective To test the effects of exercise training on
health status among patients with heart failure. Design, Setting, and Patients Multicenter,
randomized controlled trial among 2331 medically stable outpatients with heart failure with
left ventricular ejection fraction of 35% or less. Patients were randomized from April 2003
through February 2007. Interventions Usual care plus aerobic exercise training (n= 1172) …
