Molecular mechanisms for exercise training-induced changes in vascular structure and function: skeletal muscle, cardiac muscle, and the brain
TD Olver, BS Ferguson, MH Laughlin - Progress in molecular biology and …, 2015 - Elsevier
Compared with resting conditions, during incremental exercise, cardiac output in humans is
elevated from~ 5 to 25 L min− 1. In conjunction with this increase, the proportion of cardiac
output directed toward skeletal muscle increases from~ 20% to 85%, while blood flow to
cardiac muscle increases 500% and blood flow to specific brain structures increases nearly
200%. Based on existing evidence, researchers believe that blood flow in these tissues is
matched to the increases in metabolic rate during exercise. This phenomenon, the matching …
elevated from~ 5 to 25 L min− 1. In conjunction with this increase, the proportion of cardiac
output directed toward skeletal muscle increases from~ 20% to 85%, while blood flow to
cardiac muscle increases 500% and blood flow to specific brain structures increases nearly
200%. Based on existing evidence, researchers believe that blood flow in these tissues is
matched to the increases in metabolic rate during exercise. This phenomenon, the matching …
