Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice

OB Smeland, TW Meisingset, K Borges… - Neurochemistry …, 2012 - Elsevier
Acetyl-l-carnitine (ALCAR), the short-chain ester of carnitine, is a common dietary
supplement readily available in health food stores, claimed to improve energy levels and
muscle strength. ALCAR has numerous effects on brain and muscle metabolism, protects
against neurotoxic insults and may be an effective treatment for certain forms of depression.
However, little is known about the effect of chronic ALCAR supplementation on the brain
metabolism of healthy mice. Here, we investigated ALCAR's effect on cerebral energy and …